Table 8: Effect of warfarin and azithromycin on tumor necrosis factor-α in infected rats


Groups Treatment TNF-α (ng/mL)

1 Control 8.01± 0.4
2 Infected by E. coli 1 × 10 8 CFU 40.2 ± 8.1 *
3 Infected by E. coli + azithromycin 8.2 ± 0.2 **
4 Infected by E. coli + warfarin 44.1 ± 7.7
5 Infected by E. coli + azithromycin + warfarin 8.9 ± 0.5

Results are represented as mean ± SE ( n = 10); * p< 0.01, highly significant result from the control group; ** p< 0.01, highly significant result from the infected group